Pain Relievers (Acetaminophen - Tylenol, Excedrin, ect. / Ibuprofen - Motrin, Advil, ect.):
Painkillers such as Acetaminophen and Ibuprofen are called analgesics, which numb pain. Both can have a profound effect on other medications, the absorption of nutrients and therefore to our general health. Acetaminophen, also known as Paracetamol, is widely used in over-the-counter pain reliever and fever reducer derived from coal tar and has been shown to reduce glutathione production (the body’s master antioxidant). Acetaminophen is metabolized primarily in the kidneys with a lesser amount traveling through the liver, where a toxic by-product called N-acetyl-p-benzoquioneimine (NAPQI) is produced in response to the acetaminophen, and is extremely harmful to the liver. The side effects of acetaminophen include nausea, vomiting, loss of appetite, diarrhea, sweating, irritability, abdominal pain (particularly near the liver), yellow eyes or skin, liver or kidney failure, heart problems and seizures. Ibuprofen reduces melatonin levels and may affect sleep if taken at bedtime. Other drugs that interfere with melatonin production are Valium, Xanax, diuretics, beta-blockers, calcium channel blockers, alcohol and caffeine. Ibuprofen may also exacerbate anxiety and depression by causing a disruption in the hormone system that participates in the contraction and relaxation of the muscles, blood vessels and modulates inflammation. Side effects include rash, riming of the ears, headaches, dizziness, abdominal pain, nausea, diarrhea, constipation, heartburn, bruising, tingling, numbness, nervousness, depression and insomnia.